PROSPECTUS SUPPLEMENT                         FILED PURSUANT TO RULE 424(b)(3)
(TO PROSPECTUS DATED OCTOBER 5, 2004)         REGISTRATION NO. 333-118922



                         ADVANCED MEDICAL OPTICS, INC.

                                  $350,000,000

              2.50% CONVERTIBLE SENIOR SUBORDINATED NOTES DUE 2024
                                      AND
          SHARES OF COMMON STOCK ISSUABLE UPON CONVERSION OF THE NOTES



         This prospectus supplement supplements the prospectus dated October 5,
2004, as supplemented by the prospectus supplement dated October 19, 2004,
relating to the resale by certain of our securityholders of up to $350,000,000
aggregate principal amount at maturity of our 2.50% Convertible Senior
Subordinated Notes due 2024 and the shares of our common stock issuable upon
conversion of the notes. You should read this prospectus supplement in
conjunction with the prospectus. This prospectus supplement is qualified by
reference to the prospectus, except to the extent that the information in this
prospectus supplement supersedes the information contained in the prospectus.

         The information appearing under the heading "Selling Securityholders"
in the prospectus is hereby amended by the addition or substitution, as
applicable, of the following:




                                                         PERCENTAGE        NUMBER OF
                                            AGGREGATE     OF AGGREGATE     SHARES OF    PERCENTAGE
                                            PRINCIPAL      PRINCIPAL        COMMON       OF COMMON
                                            AMOUNT OF     AMOUNT             STOCK         STOCK
                                           NOTES THAT    OF NOTES         THAT MAY BE   OUTSTANDING
NAME OF SELLING SECURITYHOLDER             MAY BE SOLD    OUTSTANDING       SOLD(1)        (2) 
----------------------------------------- -------------- --------------- -------------- ------------
                                                                                    
BNP Paribas Equity Strategies, SNC (5)        3,023,000           0.86%         60,171        0.16%
CooperNeff Convertible Strategies
    (Cayman) Master Fund, LP...........       2,535,000           0.72%         50,458        0.14%
Lyxor/Convertible Arbitrage Fund
    Limited............................         517,000           0.15%         10,291            *
Newport Alternative Income Fund (6)....         910,000           0.26%         18,113            *
Silvercreek Limited Partnership (7)....       3,436,000           0.98%         68,392        0.19%
Silvercreek II Limited (8).............       2,654,000           0.76%         52,827        0.14%
Singlehedge US Convertible Arbitrage
    Fund...............................         803,000           0.23%         15,983            *
Sturgeon Limited.......................         622,000           0.18%         12,381            *
SuttonBrook Capital Portfolio LP.......       2,000,000           0.57%         39,809        0.11%
The Drake Offshore Master Fund, Ltd. (9)     14,975,000           4.28%        298,070        0.81%

Total................................      $350,000,000         100.00%      6,966,575(3)    16.0%(4)
                                           ============         =======      ============    ========

---------------------
*        Represents less than 0.1%.

(1)      Assumes conversion of all of the holder's notes at a conversion rate of 19.9045 shares of
         common stock per $1,000 principal amount at maturity of the notes. This conversion rate is
         subject to adjustment, however, as described under "Description of the Notes -- Conversion
         Rights." As a result, the number of shares of common stock issuable upon conversion of the
         notes may increase or decrease in the future.

(2)      Calculated based on Rule 13d-3(d)(i) of the Exchange Act, using 36,714,366 common shares
         outstanding as of October 27, 2004. In calculating this amount for each holder, we treated
         as outstanding the number of shares of common stock issuable upon conversion of all that
         holder's notes, but we did not assume conversion of any other holder's notes.

(3)      Represents the number of shares of common stock into which $350,000,000 aggregate principal
         amount of notes would be convertible at the conversion rate described in footnote 1 above.

(4)      Represents the amount which the selling securityholders may sell under this prospectus
         divided by the sum of the common stock outstanding as of October 27, 2004, plus the
         6,966,575 shares of common stock into which the $350,000,000 aggregate principal amount of
         notes is convertible.

(5)      Selling securityholder has identified itself as an affiliate of a broker-dealer. Each such
         selling securityholder has informed us that: (1) such selling securityholder purchased its
         notes in the ordinary course of business, and (2) at the time that the notes were
         purchased, the selling securityholder had no agreements or understandings, directly or
         indirectly, with any person to distribute the notes.

(6)      Includes $390,000 aggregate principal amount of notes previously reflected in the
         prospectus dated October 5, 2004, plus an additional $520,000 aggregate principal amount of
         notes acquired pursuant to Rule 144A of the Securities Act subsequent to September 29,
         2004, the last date information was provided to us for inclusion in such prospectus by the
         selling securityholders named therein.

(7)      Includes $1,620,000 aggregate principal amount of notes previously reflected in the
         prospectus dated October 5, 2004, plus an additional $1,816,000 aggregate principal amount
         of notes acquired pursuant to Rule 144A of the Securities Act subsequent to September 29,
         2004, the last date information was provided to us for inclusion in such prospectus by the
         selling securityholders named therein.

(8)      Includes $990,000 aggregate principal amount of notes previously reflected in the
         prospectus dated October 5, 2004, plus an additional $1,664,000 aggregate principal amount
         of notes acquired pursuant to Rule 144A of the Securities Act subsequent to September 29,
         2004, the last date information was provided to us for inclusion in such prospectus by the
         selling securityholders named therein.

(9)      Includes $11,475,000 aggregate principal amount of notes previously reflected in the
         prospectus dated October 5, 2004, plus an additional $3,500,000 aggregate principal amount
         of notes acquired pursuant to Rule 144A of the Securities Act subsequent to September 29,
         2004, the last date information was provided to us for inclusion in such prospectus by the
         selling securityholders named therein.


         INVESTING IN THE NOTES AND OUR COMMON STOCK ISSUABLE UPON CONVERSION
OF THE NOTES INVOLVES RISKS THAT ARE DESCRIBED IN THE "RISK FACTORS" SECTION OF
THE ACCOMPANYING PROSPECTUS BEGINNING ON PAGE 13.



         NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE
SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR
DETERMINED IF THIS PROSPECTUS SUPPLEMENT OR THE ACCOMPANYING PROSPECTUS IS
TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.



          The date of this prospectus supplement is November 4, 2004.