Deutsche Bank AG
Taunusanlage 12, D-60325
Frankfurt am Main
Federal Republic of Germany



Jeffrey A. Ruiz
Vice President
Telephone: (212) 250-3667


                                                                January 30, 2006

Securities and Exchange Commission
SEC Document Control
450 Fifth Street, N.W.
Washington, DC  20549
Attn:  Filing Desk


Dear Sir or Madame:

         Re:  Filing of Schedule 13G - Bio-Imaging Technologies, Inc.


Pursuant to Rule 13d-1 of the Securities Exchange Act of 1934, attached is one
copy of Schedule 13G with respect to the common stock of the above referenced
corporation.

Please acknowledge your receipt of the Schedule 13G by return e-mail
confirmation.

                                                                 Sincerely,



                                                                 Jeffrey A. Ruiz








Enclosures





                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934


                         Bio-Imaging Technologies, Inc.
                     ---------------------------------------
                                 NAME OF ISSUER:


                        Common Stock (Par Value $ 0.001)
                     ---------------------------------------
                          TITLE OF CLASS OF SECURITIES


                                    09056N103
                      -------------------------------------
                                  CUSIP NUMBER


                                December 30, 2005
                     ---------------------------------------
             (Date of Event Which Requires Filing of this Statement)


            Check the appropriate box to designate the rule pursuant
                        to which this Schedule is filed:

                               [x ] Rule 13d-1(b)

                                [ ] Rule 13d-1(c)

                                [ ] Rule 13d-1(d)





1. NAME OF REPORTING PERSONS
   S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

    Deutsche Bank AG*

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
    (A) [ ]
    (B) [ ]

3. SEC USE ONLY

4. CITIZENSHIP OR PLACE OF ORGANIZATION

     Federal Republic of Germany

NUMBER OF         5.       SOLE VOTING POWER
SHARES                     600,023
BENEFICIALLY      6.       SHARED VOTING POWER
OWNED BY                   0
EACH              7.       SOLE DISPOSITIVE POWER
REPORTING                  600,023
PERSON WITH       8.       SHARED DISPOSITIVE POWER
                           0

9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      600,023

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES  [  ]

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     5.38%

12. TYPE OF REPORTING PERSON

     HC, CO, BK

     * In accordance with Securities Exchange Act Release No. 39538 (January 12,
     1998), this filing reflects the securities beneficially owned by the
     Corporate and Investment Banking business group and the Corporate
     Investments business group (collectively, "CIB") of Deutsche Bank AG and
     its subsidiaries and affiliates (collectively, "DBAG"). This filing does
     not reflect securities, if any, beneficially owned by any other business
     group of DBAG. Consistent with Rule 13d-4 under the Securities Exchange Act
     of 1934 ("Act"), this filing shall not be construed as an admission that
     CIB is, for purposes of Section 13(d) under the Act, the beneficial owner
     of any securities covered by the filing. Furthermore, CIB disclaims
     beneficial ownership of the securities beneficially owned by (i) any client
     accounts with respect to which CIB or its employees have voting or
     investment discretion, or both, and (ii) certain investment entities, of
     which CIB is the general partner, managing general partner, or other
     manager, to the extent interests in such entities are held by persons other
     than CIB.





1. NAME OF REPORTING PERSONS
     S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

     Deutsche Bank AG, London Branch

2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP 
     (A) [ ]
     (B) [ ]

3. SEC USE ONLY

4. CITIZENSHIP OR PLACE OF ORGANIZATION

     Federal Republic of Germany

NUMBER OF         5.       SOLE VOTING POWER
SHARES                     600,023
BENEFICIALLY      6.       SHARED VOTING POWER
OWNED BY                   0
EACH              7.       SOLE DISPOSITIVE POWER
REPORTING                  600,023
PERSON WITH       8.       SHARED DISPOSITIVE POWER
                           0

9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     600,023

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES [ ]

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     5.38%

12. TYPE OF REPORTING PERSON

     CO, BK





Item 1(a).        Name of Issuer:
                  Bio-Imaging Technologies ("Issuer")

Item 1(b).        Address of Issuer's Principal Executive Offices:

                  826 Newtown - Yardley Road
                  Newtown, PA 18940-1721

Item 2(a).        Name of Person Filing:

                  This statement is filed on behalf of Deutsche Bank AG
                  ("Reporting Person").

Item 2(b).        Address of Principal Business Office or, if none, Residence:

                  Taunusanlage 12
                  D-60325 Frankfurt am Main
                  Federal Republic of Germany

Item 2(c).        Citizenship:

                  The citizenship of the Reporting Person is set forth on the
                  cover page.

Item 2(d).        Title of Class of Securities:

                  The title of the securities is common stock, $0.001 par value
                  ("Common Stock").

Item 2(e).        CUSIP Number:

                  The CUSIP number of the Common Stock is set forth on the cover
                  page.

Item 3.           If this statement is filed pursuant to Rules 13d-1(b), or 
                  13d-2(b) or (c), check whether the person filing is a:

                  (a) [ ] Broker or dealer registered under section 15 of the
                          Act;

                  (b) [X] Bank as defined in section 3(a)(6) of the Act;

                          Deutsche Bank AG, London Branch

                  (c) [ ] Insurance Company as defined in section 3(a)(19) of
                          the Act;

                  (d) [ ] Investment Company registered under section 8 of the 
                          Investment Company Act of 1940;

                  (e) [ ] An investment adviser in accordance with Rule 13d-
                          1(b)(1)(ii)(E);

                  (f) [ ] An employee benefit plan, or endowment fund in
                          accordance with Rule 13d-1 (b)(1)(ii)(F);

                  (g) [X] Parent holding company or control person in
                            accordance with Rule 13d-1 (b)(1)(ii)(G);

                           Deutsche Bank AG

                  (h) [ ]  A savings association as defined in section 3(b)
                           of the Federal Deposit Insurance Act;

                  (i) [ ]  A church plan that is excluded from the
                           definition of an investment company under section
                           3(c)(14) of the Investment Company Act of 1940;

                  (j) [ ]  Group, in accordance with Rule 13d-1
                           (b)(1)(ii)(J).



Item 4.           Ownership.

                  (a) Amount beneficially owned:

                      The Reporting Person owns the amount of the Common
                      Stock as set forth on the cover page.

                  (b) Percent of class:

                      The Reporting Person owns the percentage of the
                      Common Stock as set forth on the cover page.

                  (c) Number of shares as to which such person has:

                            (i) sole power to vote or to direct the vote:

                                    The Reporting Person has the sole power to
                                    vote or direct the vote of the Common Stock
                                    as set forth on the cover page.

                           (ii) shared power to vote or to direct the vote:

                                    The Reporting Person has the shared power to
                                    vote or direct the vote of the Common Stock
                                    as set forth on the cover page.

                           (iii) sole power to dispose or to direct the
                                 disposition of:

                                    The Reporting Person has the sole power to
                                    dispose or direct the disposition of the
                                    Common Stock as set forth on the cover page.

                           (iv) shared power to dispose or to direct the
                                disposition of:

                                    The Reporting Person has the shared power to
                                    dispose or direct the disposition of the
                                    Common Stock as set forth on the cover page.

Item 5.           Ownership of Five Percent or Less of a Class.

                  Not applicable.

Item 6.           Ownership of More than Five Percent on Behalf of Another 
                  Person.

                  Not applicable.

Item 7.           Identification and Classification of the Subsidiary Which 
                  Acquired the Security Being Reported on by the Parent Holding 
                  Company.

                  Subsidiary                            Item 3Classification

                  Deutsche Bank AG, London Branch               Bank


Item 8.           Identification and Classification of Members of the Group.

                  Not applicable.

Item 9.           Notice of Dissolution of Group.

                  Not applicable.

Item 10.          Certification.

                  By signing below I certify that, to the best of my knowledge
                  and belief, the securities referred to above were acquired and
                  are held in the ordinary course of business and were not
                  acquired and are not held for the purpose of or with the
                  effect of changing or influencing the control of the issuer of
                  the securities and were not acquired and are not held in
                  connection with or as a participant in any transaction having
                  that purpose or effect.






                                    SIGNATURE

                  After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.


Dated:  January 30, 2006



                                                    Deutsche Bank AG

                                                    By:  /s/ Jeffrey A. Ruiz
                                                    Name:    Jeffrey A. Ruiz
                                                    Title:   Vice President

                                                    By:  /s/ Pasquale Antolino
                                                    Name:    Pasquale Antolino
                                                    Title:   Associate