SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                   ----------


                    Under the Securities Exchange Act of 1934

                                  SCHEDULE 13G


             INFORMATION STATEMENT PURSUANT TO RULES 13d-1 AND 13d-2
                    UNDER THE SECURITIES EXCHANGE ACT OF 1934





                           IR BIOSCIENCES HOLDINGS, INC.
                              --------------------
                                (Name of Issuer)



                     Common Stock, $.001 par value per share
                     ---------------------------------------
                         (Title of Class of Securities)



                                    46264M303
                                  ------------
                                 (CUSIP Number)

                                  August 25, 2008
             ------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

         |_|  Rule 13d-1(b)
         |X| Rule 13d-1(c)
         |_| Rule 13d-1(d)


                               Page 1 of 2 Pages







                                  SCHEDULE 13G

CUSIP No. 46264M303                                         Page 2 of 2 Pages
-------------------------------------------------------------------------------
1)  NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

    BRENCOURT ADVISORS, LLC      EIN # 13-4137530
-------------------------------------------------------------------------------
2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)   |_|

                                                             (b)   |X|
-------------------------------------------------------------------------------
3)  SEC USE ONLY


-------------------------------------------------------------------------------
4)  CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware
-------------------------------------------------------------------------------
                                5)     SOLE VOTING POWER

       NUMBER                          0
       OF                     --------------------------------------------------
       SHARES                   6)     SHARED VOTING POWER
       BENEFICIALLY
       OWNED BY                        1,163,959
       EACH                   --------------------------------------------------
       REPORTING                7)     SOLE DISPOSITIVE POWER
       PERSON
       WITH                            0
                              --------------------------------------------------
                                8)     SHARED DISPOSITIVE POWER

                                       1,163,959
-------------------------------------------------------------------------------
9)  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

   1,163,959
-------------------------------------------------------------------------------
10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                           |_|
-------------------------------------------------------------------------------
11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

    9.98%
-------------------------------------------------------------------------------
12) TYPE OF REPORTING PERSON

    IA
-------------------------------------------------------------------------------
 


CUSIP No. 46264M303
-------------------------------------------------------------------------------
1)  NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

    Brencourt Multi-Strategy Master, Ltd.          EIN # 03-0453123
-------------------------------------------------------------------------------
2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)   |_|

                                                             (b)   |X|
-------------------------------------------------------------------------------
3)  SEC USE ONLY


-------------------------------------------------------------------------------
4)  CITIZENSHIP OR PLACE OF ORGANIZATION

    Bermuda
-------------------------------------------------------------------------------
                                5)     SOLE VOTING POWER

       NUMBER                          0
       OF                     --------------------------------------------------
       SHARES                   6)     SHARED VOTING POWER
       BENEFICIALLY
       OWNED BY                        500,502
       EACH                   --------------------------------------------------
       REPORTING                7)     SOLE DISPOSITIVE POWER
       PERSON
       WITH                            0
                              --------------------------------------------------
                                8)     SHARED DISPOSITIVE POWER

                                       500,502
-------------------------------------------------------------------------------
9)  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    500,502
-------------------------------------------------------------------------------
10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                           |_|
-------------------------------------------------------------------------------
11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

    4.29%
-------------------------------------------------------------------------------
12) TYPE OF REPORTING PERSON

    CO
-------------------------------------------------------------------------------


CUSIP No. 46264M303
-------------------------------------------------------------------------------
1)  NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

     MAN MAC Schreckhorn 14B Limited                      EIN #
-------------------------------------------------------------------------------
2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)   |_|

                                                             (b)   |X|
-------------------------------------------------------------------------------
3)  SEC USE ONLY


-------------------------------------------------------------------------------
4)  CITIZENSHIP OR PLACE OF ORGANIZATION

    Bermuda
-------------------------------------------------------------------------------
                                5)     SOLE VOTING POWER

       NUMBER                          0
       OF                     --------------------------------------------------
       SHARES                   6)     SHARED VOTING POWER
       BENEFICIALLY
       OWNED BY                        651,817
       EACH                   --------------------------------------------------
       REPORTING                7)     SOLE DISPOSITIVE POWER
       PERSON
       WITH                            0
                              --------------------------------------------------
                                8)     SHARED DISPOSITIVE POWER

                                       651,817
-------------------------------------------------------------------------------
9)  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    651,817
-------------------------------------------------------------------------------
10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                           |_|
-------------------------------------------------------------------------------
11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

    5.59%
-------------------------------------------------------------------------------
12) TYPE OF REPORTING PERSON

    CO
-------------------------------------------------------------------------------


CUSIP No. 46264M303
-------------------------------------------------------------------------------
1)  NAME OF REPORTING PERSON
    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

    Brencourt Enhanced Multi-Strategy Dedicated Fund L.P.   EIN #
-------------------------------------------------------------------------------
2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a)   |_|

                                                             (b)   |X|
-------------------------------------------------------------------------------
3)  SEC USE ONLY


-------------------------------------------------------------------------------
4)  CITIZENSHIP OR PLACE OF ORGANIZATION

    Cayman Islands
-------------------------------------------------------------------------------
                                5)     SOLE VOTING POWER

       NUMBER                          0
       OF                     --------------------------------------------------
       SHARES                   6)     SHARED VOTING POWER
       BENEFICIALLY
       OWNED BY                        11,640
       EACH                   --------------------------------------------------
       REPORTING                7)     SOLE DISPOSITIVE POWER
       PERSON
       WITH                            0
                              --------------------------------------------------
                                8)     SHARED DISPOSITIVE POWER

                                       11,640
-------------------------------------------------------------------------------
9)  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    11,640
-------------------------------------------------------------------------------
10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                           |_|
-------------------------------------------------------------------------------
11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

    0.10%
-------------------------------------------------------------------------------
12) TYPE OF REPORTING PERSON

    PN
-------------------------------------------------------------------------------


Schedule 13G

Item 1(a).

Name of Issuer: IR Biosciences Holdings, INC.

Item 1(b).   Address of Issuer's Principal Executive Offices:

8767 E. Via De Ventura, Suite 190
Scottsdale, AZ 85258

Item 2(a).   Name of Persons Filing:

Brencourt Advisors, LLC
Brencourt Multi-Strategy Master, Ltd.
MAN MAC Schreckhorn 14B Limited
Brencourt Enhanced Multi-Strategy Dedicated Fund L.P.


Item 2(b).   Address of Principal Business Office or, if None, Residence:

The principal office of Brencourt Advisors, LLC is:

600 Lexington Avenue
8th Floor
New York, NY 10022

Item 2(c).   Citizenship:

Brencourt Advisors, LLC - Delaware
Brencourt Multi-Strategy Master, Ltd. - Bermuda
MAN MAC Schreckhorn 14B Limited - Bermuda
Brencourt Enhanced Multi-Strategy Dedicated Fund L.P. - Cayman Islands

Item 2(d).   Title of Class of Securities:

Common Stock, $0.001 par value per share

Item 2(e).   CUSIP Number:

46264M303

Item 3.      If this statement is filed pursuant to ss.ss. 240.13d-1(b), or
             240.13d-2(b) or (c), check whether the person filing is a:

            (a)   |_| Broker or Dealer Registered Under Section 15 of the Act
                  (15 U.S.C. 78o)

            (b)   |_| Bank as defined in section 3(a)(6) of the Act (15 U.S.C.
                  78c)


            (c)   |_| Insurance Company as defined in section 3(a)(19) of the
                  Act (15 U.S.C. 78c)

            (d)   |_| Investment Company registered under section 8 of the
                  Investment Company Act of 1940 (15 U.S.C. 80a-8)

            (e)   |X| Investment Adviser in accordance with ss.
                  240.13d-1(b)(1)(ii)(E)

            (f)   |_| Employee benefit plan or endowment fund in accordance with
                  ss. 240.13d-1(b)(1)(ii)(F)

            (g)   |_| Parent Holding Company or control person in accordance
                  with ss.240.13d-1(b)(ii)(G)

            (h)   |_| Savings Association as defined in ss.3(b) of the Federal
                  Deposit Insurance Act (12 U.S.C. 1813)

            (i)   |_| Church plan that is excluded from the definition of an
                  investment company under ss.3(c)(15) of the Investment Company
                  Act of 1940 (15 U.S.C. 80a-3)

            (j)   |_| Group, in accordance with ss.240.13d-1(b)(ii)(J)

Item 4.      Ownership.


            (a)   Amount beneficially owned: 1,163,959

            (b)   Percent of class: 9.98%

            (c)   Number of shares as to which such person has:

                  (i)   Sole power to vote or to direct the vote:

			0

                  (ii)  Shared power to vote or to direct the vote:

			1,163,959

                  (iii) Sole power to dispose or to direct the disposition of:
                        0

                  (iv)  Shared power to dispose or to direct the disposition of:
                        1,163,959

--------------
(1) Percentages are based on 11,622,916 shares of Common Stock outstanding as of
August 7, 2008 (as set forth on the Issuer's Form 10-Q, filed on August 14,
2008 with the Securities and Exchange Commission).




Item 5.    [ ] Ownership of Five Percent or Less of a Class.


Not applicable.

Item 6.      Ownership of More than Five Percent on Behalf of Another Person.

Various persons have the right to receive or the power to direct the receipt
of dividends from, or the proceeds from the sale of, the shares of IR
Biosciences Holdings, Inc.  The Investment Manager is the investment advisor
to MAN MAC Schreckhorn 14B Limited.  Accordingly, MAN MAC Schreckhorn 14B
Limited has the right to receive and the power to direct receipt of dividends
from, or the proceeds from the sale of, the shares reported in the
corresponding Item 9 above, which represent greater than 5% of the shares
outstanding.

Item 7.      Identification and Classification of the Subsidiary Which Acquired
             the Security Being Reported on by the Parent Holding Company.

Not applicable.

Item 8.      Identification and Classification of Members of the Group.

Not applicable.

Item 9.      Notice of Dissolution of Group.

Not applicable.

Item 10.     Certification.

                  By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were acquired and are held in the
ordinary course of business and were not acquired and are not held for the
purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having such purpose or effect.






                                    SIGNATURE
                                    ----------


             After reasonable inquiry and to the best knowledge and belief of
the undersigned, the undersigned certifies that the information set forth in
this Statement is true, complete and correct.


Dated as of August 27, 2008


                             Brencourt Advisors, LLC
                             By:  Adam Hopkins
                                  Chief Compliance Officer

                             By:   /s/  Adam Hopkins
                                --------------------------------------