(Mark
One)
|
|
|
x
|
ANNUAL
REPORT PURSUANT TO SECTION 13 OR 15(d)
OF
THE SECURITIES EXCHANGE ACT OF
1934
|
o
|
TRANSITION
REPORT PURSUANT TO SECTION 13 OR 15(d)
OF
THE SECURITIES EXCHANGE ACT OF
1934
|
Delaware
|
52-2243564
|
|
(State
or Other Jurisdiction of
Incorporation
or Organization)
|
(I.R.S.
Employer
Identification
No.)
|
|
6707
Democracy Boulevard, Suite 505
Bethesda,
MD
|
20817
|
|
(Address
of Principal Executive Offices)
|
(Zip
Code)
|
Title
of Each Class
|
Name
of Each Exchange on Which Registered
|
|
Common
Stock, par value $0.00004 per share,
including
associated Series A Junior
Participating
Preferred Stock Purchase Rights
|
Nasdaq
Global Market
|
Large accelerated filer o
|
Accelerated filer x
|
Non-accelerated filer o
(Do not check if a smaller reporting company)
|
Smaller reporting company o
|
Plan Category
|
Number of Securities to Be
Issued Upon Exercise of
Outstanding Options,
Warrants and Rights
(a)
|
Weighted-Average
Exercise Price of
Outstanding
Options,
Warrants
and Rights
(b)
|
Number of Securities
Remaining Available
for Issuance Under
Equity
Compensation Plans
(Excluding Securities
Reflected in Column
(a))
(c)
|
|||||||||
Equity
compensation plans approved by security
holders(1)
|
7,723,313 | $ | 3.58 | 1,035,778 | ||||||||
Equity
compensation plans not approved by security holders(2)
|
1,328,276 | $ | 2.94 | 292,099 | ||||||||
Total
|
9,051,589 | $ | 3.48 | 1,327,877 |
(1)
|
Includes
the 2003 Amended and Restated Equity Incentive Plan and the Employee Stock
Purchase Plan. On January 1 of each year during the initial ten-year term
of the 2003 Amended and Restated Equity Incentive Plan, the number of
shares which may be issued under such plan is increased by the least of
(i) five percent (5%) of the Company's outstanding shares on such date,
(ii) 2,500,000 shares or (iii) a lesser amount determined by the board. No
shares are currently outstanding under the Employee Stock Purchase Plan
and 234,819 shares remain available under that
plan.
|
(2)
|
Consists
of the 2006 Equity Incentive Award Plan and the Third Amended and Restated
2000 Stock Incentive Award Plan.
|
Exhibit
Number
|
Description
|
|
3.1(5)
|
Amended
and Restated Certificate of Incorporation of the
Registrant
|
|
3.2(13)
|
Certificate
of Amendment of the Amended and Restated Certificate of Incorporation of
the Registrant
|
|
3.3(7)
|
Certificate
of Designations of Series A Junior Participating Preferred Stock of the
Registrant
|
|
3.4(22)
|
Amended
and Restated Bylaws effective October 3, 2007
|
|
4.1(28)
|
Form
of Specimen Common Stock Certificate
|
|
4.2(7)
|
Rights
Agreement, by and between the Registrant and American Stock Transfer &
Trust Company, LLC, which includes the form of Certificate of Designations
of the Series A Junior Participating Preferred Stock of the Registrant as
Exhibit A, the form of Right Certificate as Exhibit B and the Summary of
Rights to Purchase Preferred Shares as Exhibit C, dated as of November 3,
2004
|
4.3(10)
|
First
Amendment to Rights Agreement, by and between the Registrant and American
Stock Transfer & Trust Company, LLC, dated as of March 17,
2006
|
|
4.4(18)
|
Form
of Warrant to Purchase Common Stock, dated May 5, 2006
|
|
4.5(14)
|
Form
of Warrants to purchase an aggregate of 555,556 shares of Common Stock, in
favor of funds affiliated with NGN Capital, LLC, dated July 24,
2006
|
|
4.6(20)
|
Warrant
to Purchase Common Stock, dated June 19, 2007
|
|
4.7(20)
|
Alternate
Warrant to Purchase Common Stock, dated June 19, 2007
|
|
4.8(25)
|
Form
of Warrant to Purchase Common Stock dated October 2,
2008
|
|
4.9(25)
|
Alternate
Form of Warrant to Purchase Common Stock dated October 2,
2008
|
|
4.10(26)
|
Common
Stock Purchase Agreement dated December 1, 2008 between the Registrant and
Kingsbridge Capital Limited
|
|
4.11(26)
|
Registration
Rights Agreement dated December 1, 2008 between the Registrant and
Kingsbridge Capital Limited
|
|
4.12(16)
|
Warrant
to purchase 285,000 shares of Common Stock, issued to Kingsbridge Capital
Limited, dated August 30, 2006
|
|
4.13(26)
|
Warrant
to Purchase Common Stock dated December 1, 2008 and issued to Kingsbridge
Capital Limited
|
|
10.1(17)(#)
|
Executive
Employment Agreement, by and between the Registrant and Christian Itin,
dated June 2, 2006
|
|
10.2(24)(#)
|
Executive
Employment Agreement, by and between the Registrant and Barclay Phillips,
dated August 30, 2008
|
|
10.3(27)(#)
|
Amendment
No. 1 to Executive Employment Agreement, by and between the Registrant and
Barclay Phillips, dated November 18, 2008
|
|
10.4(27)(#)
|
Amendment
No. 2 to Executive Employment Agreement, by and between the Registrant and
Barclay Phillips, dated December 23, 2008
|
|
10.5(27)(#)
|
Amended
and Restated Executive Employment Agreement, by and between the Registrant
and Matthias Alder, dated December 23, 2008
|
|
10.6(27)(#)
|
Amended
and Restated Executive Employment Agreement, by and between the Registrant
and Mark Reisenauer, dated December 23, 2008
|
|
10.7(32)(#)
|
Executive
Employment Agreement, by and between the Registrant and Jan Fagerberg,
dated September 17, 2009
|
|
10.8(18)(#)
|
Executive
Employment Agreement, by and between the Registrant and Jens Hennecke,
dated June 2, 2006
|
|
10.9(18)(#)
|
Executive
Employment Agreement, by and between the Registrant and Patrick Baeuerle,
dated June 2, 2006
|
|
10.10(30)(#)
|
Separation
Agreement by and between the Registrant and Carsten Reinhardt, dated July
6, 2009
|
|
10.11(28)(#)
|
2009
Management Incentive Compensation Plan
|
|
10.12(29)(#)
|
Non-Employee
Director Compensation Policy
|
|
10.13(2)(#)
|
Third
Amended and Restated 2000 Stock Incentive Plan
|
|
10.14(4)(#)
|
Employee
Stock Purchase Plan
|
|
10.15(31)(#)
|
Amended
and Restated 2003 Equity Incentive Award Plan
|
|
10.16(18)(#)
|
2006
Equity Incentive Award Plan
|
|
10.17(2)(#)
|
Form
of Indemnification Agreement entered into by the Registrant with its
directors and executive officers
|
|
10.18(21)
|
Office
Building Lease Agreement dated April 1, 2007 between Micromet, Inc. and
Second Rock Spring Park Limited Partnership
|
|
10.19(18)(@)
|
Lease
Agreement by and between Micromet AG and GEK
Grundstücksverwaltungsgesellschaft mbH & Co. Objekt Eins KG, dated
December 10, 2002, as amended
|
|
10.20(21)(&)
|
Sublease
Agreement, dated June 15, 2007, by and between Micromet AG and Roche
Diagnostics GmBH
|
|
10.21(32)(@)
|
Lease
Agreement by and between Micromet AG and KFV Immobilienverwaltungs GmbH,
dated November 4, 2009
|
|
10.22(1)
|
Standard
Industrial/Commercial Single-Tenant Lease-Net, by and between the
Registrant and Blackmore Airport Centre, dated August 31,
2001
|
10.23(12)
|
Sublease
Agreement, by and between the Registrant and Genoptix, Inc., dated as of
April 26, 2006
|
|
10.24(19)
|
Amendment
No. 1 to Sublease dated April 2, 2007 by and between Micromet, Inc. and
Genoptix, Inc.
|
|
10.25(1)
|
Lease,
by and between Spieker Properties, L.P. and John Wayne Cancer Institute,
made as of July 22, 1999
|
|
10.26(1)
|
Agreement
of Lease Assignment, by and between the Registrant and John Wayne Cancer
Institute, dated as of August 4, 2000
|
|
10.27(1)
|
First
Amendment to Lease, by and between the Registrant (as successor in
interest to John Wayne Cancer Institute) and EOP — Marina Business Center,
L.L.C. (as successor in interest to Spieker Properties, L.P.), entered
into as of October 1, 2001
|
|
10.28(1)
|
Second
Amendment to Lease, by and between the Registrant and EOP — Marina
Business Center, L.L.C., entered into as of September 4,
2002
|
|
10.29(8)
|
Third
Amendment to Lease, by and between the Registrant and CA-Marina Business
Center Limited Partnership, entered into as of November 14,
2003
|
|
10.30(9)
|
Fourth
Amendment to Lease, by and between the Registrant and Marina Business
Center, LLC, entered into as of January 18, 2005
|
|
10.31(13)
|
Fifth
Amendment to Lease, by and among the Registrant, Marina Business Center,
LLC, and American Bioscience, Inc., dated as of April 18,
2006
|
|
10.32(11)
|
Assignment
and Assumption of Lease, by and between the Registrant and American
Bioscience, Inc., effective as of May 1, 2006
|
|
10.33(+)
|
Termination
and License Agreement, by and between MedImmune, LLC and Micromet AG,
dated as of November 4, 2009
|
|
10.34(+)
|
Development
and Supply Agreement, by and between Lonza Sales AG and Micromet AG, dated
as of November 23, 2009
|
|
10.35(18)(%)
|
BiTE
Research Collaboration Agreement, by and between Micromet AG and
MedImmune, Inc., dated June 6, 2003
|
|
10.36(28)(%)
|
Option,
Collaboration and License Agreement, by and between Micromet AG and Bayer
Schering Pharma AG, dated January 12, 2009
|
|
10.37(+)
|
Amendment
No. 1 to Option, Collaboration and License Agreement, by and between
Micromet AG and Bayer Schering Pharma AG, dated as of November 25,
2009
|
|
10.38(+)
|
Collaboration
and License Agreement, by and between Micromet AG and sanofi-aventis,
dated October 28, 2009
|
|
10.39(21)(%)
|
Collaboration
and License Agreement, dated May 24, 2007, by and between Micromet AG and
Altana Pharma AG, a wholly-owned subsidiary of Nycomed
A/S
|
|
10.40(19)(%)
|
License
Agreement dated March 14, 2007 by and between Cell-Matrix, Inc. and TRACON
Pharmaceuticals, Inc.
|
|
10.41(18)(%)
|
Collaboration
and License Agreement, by and between Micromet AG and Ares Trading S.A.,
dated as of December 3, 2004, as amended on November 30,
2006
|
|
10.42(23)(%)
|
Second
Amendment to Collaboration and License Agreement dated October 19, 2007 by
and between Micromet AG and Merck Serono International
SA
|
|
10.43(18)(%)
|
Research
and License Agreement, by and between Micromet AG and Biovation Limited,
dated August 14, 2001, as amended on September 26, 2002 and June 16,
2004
|
|
10.44(18)(%)
|
Non-Exclusive
Product License Agreement for MT201, by and between Micromet AG and
Cambridge Antibody Technology Limited, dated September 3, 2003, as amended
on March 17, 2005
|
|
10.45(18)(%)
|
Non-Exclusive
Product License Agreement for MT203, by and between Micromet AG and
Cambridge Antibody Technology Limited, dated November 3, 2003, as amended
on March 17, 2005
|
|
10.46(18)(%)
|
Amended
and Restated Cross-License Agreement, by and between Micromet AG and Enzon
Pharmaceuticals, Inc., dated June 28, 2004, as amended on March 17,
2005
|
|
10.47(18)(%)
|
GM-CSF
License Agreement, by and between Micromet AG and Enzon Pharmaceuticals,
Inc., dated November 21, 2005
|
|
10.48(6)(%)
|
Amended
and Restated Collaboration Agreement, by and between Cell-Matrix, Inc., a
wholly owned subsidiary of the Registrant, and Applied Molecular
Evolution, dated as of October 15,
2004
|
10.49(15)(%)
|
First
Amendment to Amended and Restated Collaboration Agreement, by and between
Cell-Matrix, Inc., a wholly-owned subsidiary of the Registrant, and
Applied Molecular Evolution, dated as of June 10, 2006
|
|
10.50(3)(%)
|
License
Agreement, by and between the University of Southern California and
Cell-Matrix, Inc. f/k/a Bio-Management, Inc., dated September 19,
1999
|
|
10.51(18)(%)
|
First
Amendment to License Agreement, by and between the University of Southern
California and Cell-Matrix, Inc., dated as of February 23,
2007
|
|
11.1(32)
|
Computation
of Per Share Earnings
|
|
21.1(32)
|
List
of Subsidiaries
|
|
23.1(32)
|
Consent
of Ernst & Young LLP
|
|
23.2(32)
|
Consent
of Ernst & Young GmbH WPG, formerly known as Ernst & Young AG and
Ernst & Young Deutsche Allgemeine Treuhand AG WPG
|
|
24.1(32)
|
Powers
of Attorney
|
|
31.1
|
Certification
of Principal Executive Officer pursuant to Rules 13a-14 and 15d-14
promulgated under the Securities Exchange Act of 1934
|
|
31.2
|
Certification
of Principal Financial Officer pursuant to Rules 13a-14 and 15d-14
promulgated under the Securities Exchange Act of 1934
|
|
32(32)
(*)
|
Certifications
of Principal Executive Officer and Principal Financial Officer pursuant to
18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002
|
(1)
|
Previously
filed on August 14, 2003 as an exhibit to the Registrant’s Registration
Statement on Form S-1 (Registration No. 333-107993) and incorporated by
reference herein.
|
(2)
|
Previously
filed on September 16, 2003 as an exhibit to Amendment No. 2 to the
Registrant’s Registration Statement on Form S-1 (Registration No.
333-107993) and incorporated by reference
herein.
|
(3)
|
Previously
filed on October 24, 2003 as an exhibit to Amendment No. 4 to the
Registrant’s Registration Statement on Form S-1 (Registration No.
333-107993) and incorporated by reference
herein.
|
(4)
|
Previously
filed on October 30, 2003 as an exhibit to the Registrant’s Registration
Statement on Form S-8 (Registration No. 333-110085) and incorporated by
reference herein.
|
(5)
|
Previously
filed on December 11, 2003 as an exhibit to the Registrant’s Quarterly
Report on Form 10-Q and incorporated by reference
herein.
|
(6)
|
Previously
filed on October 21, 2004 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference
herein.
|
(7)
|
Previously
filed on November 8, 2004 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference
herein.
|
(8)
|
Previously
filed on December 29, 2004 as an exhibit to the Registrant’s Current
Report on Form 8-K and incorporated by reference
herein.
|
(9)
|
Previously
filed on January 20, 2005 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference
herein.
|
(10)
|
Previously
filed on March 20, 2006 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference
herein.
|
(11)
|
Previously
filed on April 20, 2006 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference
herein.
|
(12)
|
Previously
filed on May 1, 2006 as an exhibit to the Registrant’s Current Report on
Form 8-K and incorporated by reference herein.
|
(13)
|
Previously
filed on May 10, 2006 as an exhibit to the Registrant’s Quarterly Report
on Form 10-Q and incorporated by reference
herein.
|
(14)
|
Previously
filed on July 26, 2006 as an exhibit to the Registrant’s Current Report on
Form 8-K and incorporated by reference herein.
|
(15)
|
Previously
filed on August 8, 2006 as an exhibit to the Registrant’s Quarterly Report
on Form 10-Q and incorporated by reference herein.
|
(16)
|
Previously
filed on August 31, 2006 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference herein.
|
(17)
|
Previously
filed on November 9, 2006 as an exhibit to the Registrant’s Quarterly
Report on Form 10-Q and incorporated by reference
herein.
|
(18)
|
Previously
filed on March 16, 2007 as an exhibit to the Registrant’s Annual Report on
Form 10-K and incorporated by reference herein.
|
(19)
|
Previously
filed on May 10, 2007 as an exhibit to the Registrant’s Quarterly Report
on Form 10-Q and incorporated by reference herein.
|
(20)
|
Previously
filed on June 21, 2007 as an exhibit to the Registrant’s Current Report on
Form 8-K and incorporated by reference herein.
|
(21)
|
Previously
filed on August 9, 2007 as an exhibit to the Registrant’s Quarterly Report
on Form 10-Q and incorporated by reference herein.
|
(22)
|
Previously
filed on October 9, 2007 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference herein.
|
(23)
|
Previously
filed on March 14, 2008 as an exhibit to the Registrant’s Annual Report on
Form 10-K and incorporated by reference herein.
|
(24)
|
Previously
filed on September 2, 2008 as an exhibit to the Registrant’s Current
Report on Form 8-K and incorporated by reference
herein.
|
(25)
|
Previously
filed on October 6, 2008 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference herein.
|
(26)
|
Previously
filed on December 2, 2008 as an exhibit to the Registrant’s Current Report
on Form 8-K and incorporated by reference herein.
|
(27)
|
Previously
filed on March 16, 2009 as an exhibit to the Registrant’s Annual Report on
Form 10-K and incorporated by reference herein.
|
(28)
|
Previously
filed on May 11, 2009 as an exhibit to the Registrant’s Quarterly Report
on Form 10-Q and incorporated by reference herein.
|
(29)
|
Previously
filed on August 6, 2009 as an exhibit to the Registrant’s Quarterly Report
on Form 10-Q and incorporated by reference herein.
|
(30)
|
Previously
filed on November 6, 2009 as an exhibit to the Registrant’s Quarterly
Report on Form 10-Q and incorporated by reference
herein.
|
(31)
|
Previously
filed on December 18, 2009 as an exhibit to the Registrant’s Registration
Statement on Form S-8 and incorporated by reference
herein.
|
(32)
|
Previously
filed on March 5, 2010 as an exhibit to the Registrant’s Annual Report on
Form 10-K and incorporated by reference herein.
|
&
|
Indicates
that the exhibit is an English translation of a foreign language
document.
|
@
|
Indicates
that the exhibit is an English summary of a foreign language
document.
|
#
|
Indicates
management contract or compensatory plan.
|
%
|
The
Registrant has been granted confidential treatment with respect to certain
portions of this exhibit (indicated by asterisks), which have been filed
separately with the Securities and Exchange Commission.
|
+
|
Portions
of this exhibit (indicated by asterisks) have been omitted pursuant to a
request for confidential treatment and have been separately filed with the
Securities and Exchange Commission.
|
*
|
These
certifications are being furnished solely to accompany this annual report
pursuant to 18 U.S.C. Section 1350, and are not being filed for purposes
of Section 18 of the Securities Exchange Act of 1934 and are not to be
incorporated by reference into any filing of the Registrant, whether made
before or after the date hereof, regardless of any general incorporation
language in such filing.
|
MICROMET,
INC.
|
|||
By:
|
/s/ Christian Itin
|
||
Christian Itin
|
|||
President and Chief Executive Officer
|
|||
(Principal Executive Officer)
|
|||
By:
|
/s/ Barclay A. Phillips
|
||
Barclay A. Phillips
|
|||
Senior Vice President and Chief Financial Officer
|
|||
(Principal Financial Officer)
|
|||
Dated:
July 20, 2010
|