PAGE  1
000 B000000 07/31/2012
000 C000000 0001176433
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 NUVEEN QUALITY PREFERRED INCOME FUND 2
001 B000000 811-21137
001 C000000 3129178200
002 A000000 333 WEST WACKER DRIVE
002 B000000 CHICAGO
002 C000000 IL
002 D010000 60606
002 D020000 1286
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 N
007 B000000  0
007 C010100  1
007 C010200  2
007 C010300  3
007 C010400  4
007 C010500  5
007 C010600  6
007 C010700  7
007 C010800  8
007 C010900  9
007 C011000 10
007 C011100 11
007 C011200 12
007 C011300 13
007 C011400 14
007 C011500 15
007 C011600 16
007 C011700 17
007 C011800 18
007 C011900 19
007 C012000 20
007 C012100 21
007 C012200 22
007 C012300 23
007 C012400 24
007 C012500 25
007 C012600 26
007 C012700 27
007 C012800 28
      PAGE  2
007 C012900 29
007 C013000 30
007 C013100 31
007 C013200 32
007 C013300 33
007 C013400 34
007 C013500 35
007 C013600 36
007 C013700 37
007 C013800 38
007 C013900 39
007 C014000 40
007 C014100 41
007 C014200 42
007 C014300 43
007 C014400 44
007 C014500 45
007 C014600 46
007 C014700 47
007 C014800 48
007 C014900 49
007 C015000 50
008 A000001 NUVEEN FUND ADVISOR, INC.
008 B000001 A
008 C000001 801-14147
008 D010001 CHICAGO
008 D020001 IL
008 D030001 60606
008 D040001 1286
008 A000002 NUVEEN ASSET MANAGEMENT, INC.
008 B000002 S
008 C000002 801-71957
008 D010002 CHICAGO
008 D020002 IL
008 D030002 60606
008 D040002 1286
012 A000001 COMPUTERSHARE
012 B000001 84-05925
012 C010001 PROVIDENCE
012 C020001 RI
012 C030001 02940
013 A000001 ERNST & YOUNG LLP
013 B010001 CHICAGO
013 B020001 IL
013 B030001 60606
014 A000001 NUVEEN INVESTMENTS, LLC
014 B000001 8-13464
014 A000002 SPECTRUM ASSET MANAGEMENT, INC.
014 B000002 8-36472
015 A000001 STATE STREET BANK AND TRUST COMPANY
015 B000001 C
      PAGE  3
015 C010001 BOSTON
015 C020001 MA
015 C030001 02110
015 E010001 X
018  000000 Y
019 A000000 Y
019 B000000  219
019 C000000 NUVEENFUND
020 A000001 SPECTRUM ASSET MANAGEMENT, INC.
020 B000001 06-1209521
020 C000001    124
020 C000002      0
020 C000003      0
020 C000004      0
020 C000005      0
020 C000006      0
020 C000007      0
020 C000008      0
020 C000009      0
020 C000010      0
021  000000      124
022 A000001 SPECTRUM ASSET MGMT
022 B000001 06-1209521
022 C000001    320534
022 D000001     86235
022 A000002 THORNTON FARISH
022 B000002 63-1019916
022 C000002         0
022 D000002      6010
022 A000003 JEFFERIES & CO
022 B000003 95-2622900
022 C000003      1406
022 D000003         0
022 C000004         0
022 D000004         0
022 C000005         0
022 D000005         0
022 C000006         0
022 D000006         0
022 C000007         0
022 D000007         0
022 C000008         0
022 D000008         0
022 C000009         0
022 D000009         0
022 C000010         0
022 D000010         0
023 C000000     321940
023 D000000      92245
024  000000 N
025 D000001       0
      PAGE  4
025 D000002       0
025 D000003       0
025 D000004       0
025 D000005       0
025 D000006       0
025 D000007       0
025 D000008       0
026 A000000 N
026 B000000 N
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027  000000 N
028 A010000         0
028 A020000         0
028 A030000         0
028 A040000         0
028 B010000         0
028 B020000         0
028 B030000         0
028 B040000         0
028 C010000         0
028 C020000         0
028 C030000         0
028 C040000         0
028 D010000         0
028 D020000         0
028 D030000         0
028 D040000         0
028 E010000         0
028 E020000         0
028 E030000         0
028 E040000         0
028 F010000         0
028 F020000         0
028 F030000         0
028 F040000         0
028 G010000         0
028 G020000         0
028 G030000         0
028 G040000         0
028 H000000         0
030 A000000      0
030 B000000  0.00
030 C000000  0.00
031 A000000      0
031 B000000      0
      PAGE  5
032  000000      0
033  000000      0
035  000000      0
036 B000000      0
038  000000      0
042 A000000   0
042 B000000   0
042 C000000   0
042 D000000   0
042 E000000   0
042 F000000   0
042 G000000   0
042 H000000   0
043  000000      0
044  000000      0
045  000000 Y
046  000000 N
047  000000 N
048  000000  0.000
048 A010000        0
048 A020000 0.000
048 B010000        0
048 B020000 0.000
048 C010000        0
048 C020000 0.000
048 D010000        0
048 D020000 0.000
048 E010000        0
048 E020000 0.000
048 F010000        0
048 F020000 0.000
048 G010000        0
048 G020000 0.000
048 H010000        0
048 H020000 0.000
048 I010000        0
048 I020000 0.000
048 J010000        0
048 J020000 0.000
048 K010000        0
048 K020000 0.000
049  000000 N
050  000000 N
051  000000 N
052  000000 Y
053 A000000 N
054 A000000 Y
054 B000000 N
054 C000000 N
054 D000000 N
054 E000000 N
      PAGE  6
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 Y
054 N000000 N
054 O000000 Y
055 A000000 N
055 B000000 N
056  000000 Y
057  000000 N
058 A000000 N
059  000000 Y
060 A000000 N
060 B000000 N
061  000000        0
062 A000000 N
062 B000000   0.0
062 C000000   0.0
062 D000000   0.0
062 E000000   0.0
062 F000000   0.0
062 G000000   0.0
062 H000000   0.0
062 I000000   0.0
062 J000000   0.0
062 K000000   0.0
062 L000000   0.0
062 M000000   0.0
062 N000000   0.0
062 O000000   0.0
062 P000000   0.0
062 Q000000   0.0
062 R000000   0.0
063 A000000   0
063 B000000  0.0
066 A000000 Y
066 B000000 N
066 C000000 N
066 D000000 N
066 E000000 N
066 F000000 Y
066 G000000 N
067  000000 N
068 A000000 N
068 B000000 N
069  000000 N
070 A010000 Y
      PAGE  7
070 A020000 Y
070 B010000 Y
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 Y
070 D020000 N
070 E010000 Y
070 E020000 N
070 F010000 Y
070 F020000 N
070 G010000 Y
070 G020000 N
070 H010000 Y
070 H020000 N
070 I010000 Y
070 I020000 N
070 J010000 Y
070 J020000 Y
070 K010000 Y
070 K020000 Y
070 L010000 Y
070 L020000 N
070 M010000 N
070 M020000 N
070 N010000 Y
070 N020000 N
070 O010000 Y
070 O020000 N
070 P010000 N
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000    343581
071 B000000    261018
071 C000000   1391649
071 D000000   19
072 A000000 12
072 B000000    48217
072 C000000    53450
072 D000000        0
072 E000000        0
072 F000000    11932
072 G000000        0
072 H000000        0
072 I000000        9
072 J000000      209
072 K000000       81
072 L000000      161
      PAGE  8
072 M000000       48
072 N000000        0
072 O000000        0
072 P000000     5586
072 Q000000        0
072 R000000       24
072 S000000       50
072 T000000        0
072 U000000        0
072 V000000        0
072 W000000      285
072 X000000    18385
072 Y000000        0
072 Z000000    83282
072AA000000     2705
072BB000000        0
072CC010000    35082
072CC020000        0
072DD010000    79417
072DD020000        0
072EE000000        0
073 A010000   0.6600
073 A020000   0.0000
073 B000000   0.0000
073 C000000   0.0000
074 A000000      428
074 B000000    43239
074 C000000        0
074 D000000    98811
074 E000000   720472
074 F000000        0
074 G000000        0
074 H000000        0
074 I000000   660416
074 J000000     2277
074 K000000        0
074 L000000    12470
074 M000000      221
074 N000000  1538334
074 O000000        0
074 P000000     1084
074 Q000000        0
074 R010000        0
074 R020000        0
074 R030000        0
074 R040000   439865
074 S000000        0
074 T000000  1097385
074 U010000   120352
074 U020000        0
074 V010000     9.12
      PAGE  9
074 V020000     0.00
074 W000000   0.0000
074 X000000      226
074 Y000000   498187
075 A000000        0
075 B000000  1023969
076  000000     9.34
077 A000000 Y
077 B000000 Y
077 E000000 Y
078  000000 N
080 A000000 CHUBB GROUP OF INSURANCE COMPANIES
080 B000000 BERKLEY, GREAT AMERICAN, ST.PAUL,CNA & ZURICH
080 C000000   114000
081 A000000 Y
081 B000000 218
082 A000000 N
082 B000000        0
083 A000000 N
083 B000000        0
084 A000000 N
084 B000000        0
085 A000000 Y
085 B000000 N
086 A010000      0
086 A020000      0
086 B010000     30
086 B020000    265
086 C010000      0
086 C020000      0
086 D010000      0
086 D020000      0
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
087 A010000 COMMON STOCK
087 A020000 67072C105
087 A030000 JPS
088 A000000 N
088 B000000 N
088 C000000 N
088 D000000 N
SIGNATURE   STEPHEN D. FOY
TITLE       V.P & CONTROLLER